Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial
Is Intraligamentary Injection the Anesthesia of Choice for Symptomatic Irreversible Pulpitis in Mandibular Molars? A Multicenter Randomized Comparative Trial.
Aula Dental Avanzada
52 participants
Jun 20, 2025
INTERVENTIONAL
Conditions
Summary
This multicenter randomized trial compares the clinical effectiveness of intraligamentary injection versus inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in mandibular molars. The goal is to determine which technique provides better pain control during endodontic treatment.
Eligibility
Inclusion Criteria5
- Adults aged 18 years or older
- Presenting with symptomatic irreversible pulpitis in a mandibular molar
- Vital response to cold testing
- Ability to understand and provide informed consent
- Available for follow-up and data collection
Exclusion Criteria6
- Known allergy to lidocaine or epinephrine
- Pregnancy or breastfeeding
- Use of analgesics or anti-inflammatory drugs in the previous 6 hours
- Non-vital or previously treated teeth
- Significant systemic disease (ASA III or above)
- History of psychiatric or neurological disorders affecting pain perception
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Interventions
Intraligamentary local anesthesia will be administered using a standard dental syringe with 2% lidocaine and 1:100,000 epinephrine.
Inferior alveolar nerve block will be performed with 2% lidocaine and 1:100,000 epinephrine using the conventional technique.
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT07130760