Incidence of Postoperative Cognitive Decline in Patients With Preexisting Cognitive Impairment
Incidence of Postoperative Cognitive Decline in Surgical Patients With Preexisting Cognitive Impairment: A Prospective Cohort Study
Peking University Shenzhen Hospital
340 participants
Jul 15, 2025
OBSERVATIONAL
Conditions
Summary
This study aims to find out how often memory and thinking problems happen after surgery in people who already have memory issues before their operation. These memory problems are called postoperative cognitive decline (POCD). Older adults with memory problems before surgery may be more likely to have trouble with thinking, memory, and daily activities after their operation. This study will follow patients who already have memory problems before surgery and see how their thinking and memory change after surgery. The results will help doctors better understand how to care for these patients before, during, and after surgery.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Patients with preexisting cognitive impairment undergoing elective non-cardiac surgery under general anesthesia.
Cognitively normal individuals who do not undergo surgery but complete the same cognitive assessments at baseline, 3 months, and 12 months for normative reference.
Locations(1)
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NCT07135336