RecruitingPhase 2NCT07338682

Evaluation of the Effect of L-Arginine on the Cognitive Function in Geriatric Patients

Evaluation of the Effect of L-Arginine on the Cognitive Function in Geriatric Patients, A Randomized Clinical Trial


Sponsor

German University in Cairo

Enrollment

60 participants

Start Date

Aug 27, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to evaluate the effect of L-arginine supplementation on cognitive function in geriatric patients. Eligible participants will receive either L-arginine (6 grams once daily) or placebo, and their cognitive performance will be assessed using validated cognitive assessment tools over the study period. The participants will receive the intervention for 4 weeks and followed up every 2 weeks. The primary outcome is improvement in cognitive function, while secondary outcomes include safety, tolerability, and quality of life measures. The findings may provide evidence for the potential role of L-arginine in supporting cognitive health in elderly populations.


Eligibility

Min Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying L-Arginine and Placebo for people with cognition disorders in old age and cognitive and behavioral impairment. The study is currently recruiting participants at 1 location. People eligible for this study include aged 60 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTL-Arginine

6 grams L-arginine sachets taken orally once daily

OTHERPlacebo

Matching Placebo of L-arginine


Locations(1)

Neurology Department, Al-Azhar University Hospitals

Cairo, Egypt

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NCT07338682


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