RecruitingNCT07136532

Prediction of Fluid Responsiveness in Paediatric Patients With Septic Shock Using Carotid Doppler Ultrasonography and Echocardiography


Sponsor

Ain Shams University

Enrollment

50 participants

Start Date

Sep 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this study is to evaluate the role of carotid Doppler and Echocardiography as a predictor of fluid responsiveness in paediatric patients with septic shock. and To evaluate the diagnostic accuracy of Aortic peak velocity and velocity time integral (VTI)variation in patients with septic shock during their fluid resuscitation phase as a reliable predictor of fluid responsiveness.


Eligibility

Min Age: 1 MonthMax Age: 16 Years

Inclusion Criteria2

  • Children aged 1 month to 16 years.
  • Patients with septic shock admitted at the PICU during their fluid resuscitative phase were included.Septic shock was diagnosed according to phoenix sepsis score 2024

Exclusion Criteria6

  • Acquired and congenital heart disease.
  • Acquired and congenital renal disease.
  • Vascular anomalies (e.g. arteriovenous malformation, aneurysm).
  • Suspected intracranial hypertension.
  • Skin lesions or bandages at the sites of ultrasound or echo-cardiography examinations.
  • Anatomical anomalies of the neck.

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Interventions

DIAGNOSTIC_TESTechocardiography

Echocardiography will be performed using the ultrasound system echocardiographic equipment (Siemens Advanced Clinical Ultrasound Systems Optimized Navigation (ACUSON) P500), carotid doppler ultrasonography (Carotid blood flow and Corrected flow time) by using the ultrasound system echocardiographic equipment (Siemens ACUSON P500) . Those measurements will be done at time zero and upon completion of fluid resuscitation . • Statistical Analysis: All data will be collected, tabulated, and statistically analysed using International Business Machines\_Statistical Package for the Social Sciences (IBM SPSS) version 27.


Locations(1)

Ain shams university _faculty of medicine

Cairo, Egypt

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NCT07136532


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