RecruitingNot ApplicableNCT07145073

Repetitive Transcranial Alternating Current Stimulation (rtACS) for the Treatment of Optic Neuropathies

Repetitive Transcranial Alternating Current Stimulation(rtACS) for the Treatment of Optic Neuropathies


Sponsor

National Taiwan University Hospital

Enrollment

188 participants

Start Date

Jan 26, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to see whether repeated transcranial alternating current stimulation can activate impaired retinal ganglion cells and improve both structural and functional outcomes in patients with glaucoma.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a non-invasive brain stimulation technique — repetitive transcranial alternating current stimulation (rtACS), which uses gentle electrical currents applied to the head — can improve vision in people with glaucoma-related visual field loss. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with glaucoma with moderate visual field loss (within a specific range) - Your visual acuity (best corrected eyesight) in the eye being treated is at least 0.2 - Your eye pressure is considered stable by your doctor - You are able to attend all study visits and follow the schedule **You may NOT be eligible if...** - You have a history of eye herpes, retinal disease, corneal opacity, cataracts affecting vision, or uveitis - You have a pacemaker or other electronic implant - You have an autoimmune or rheumatologic disease - You have a brain tumor, metal in the head, or a history of epilepsy or cranial surgery - You have significant anxiety, claustrophobia, or dementia - You are pregnant or breastfeeding - You have had prior electrical stimulation of the eyes or visual training studies in the past year - You have uncontrolled hypertension or diabetes Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEDC-Stimulator MC

Experimental:Participants will receive 10 days of repeated transcranial alternating current stimulation treatment in hospital.

DEVICEDC-Stimulator MC

Sham Comparator:Participants will receive 10 days of repeated transcranial alternating current stimulation treatment (no active stimulation) in hospital.


Locations(1)

National Taiwan University Hospital

Taipei, Hawaii, Taiwan

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NCT07145073


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