Pregnancies Before the Diagnosis of Systemic Lupus Erythematosus
Pregnancy Outcomes Prior to a Systemic Lupus Erythematosus Diagnosis
University of Algiers
50 participants
Jan 1, 2025
OBSERVATIONAL
Conditions
Summary
This is an observational, monocentric, retrospective cohort study. Its primary objective is to examine maternal and foetal outcomes in pregnancies that occurred before the diagnosis of systemic lupus erythematosus (SLE) in a group of female participants who were subsequently diagnosed with the condition.
Eligibility
Inclusion Criteria4
- Women of childbearing age with a history of at least one pregnancy
- Pregnancy occurred before the diagnosis of LES.
- LES was diagnosed after at least one pregnancy.
- The subject is classified as having LES according to the 1997 ACR or EULAR 2019 criteria.
Exclusion Criteria1
- LES was previously diagnosed prior to any conception.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
For participants who are still alive, data are collected from interviews with patients using a prepared questionnaire that asks about all pregnancies and obstetrical events prior to the diagnosis of SLE. For deceased patients, data are taken from the medical records of obstetrical events. Data will be collected on anthropometric, biological, immunological, and histological features before and after the diagnosis of SLE, if available. The activity and severity of the disease after diagnosis will be assessed using the recommended tools.
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07148115