Colorectal Analysis for Signature Cancer Assessment Using Delta-HLD

This study is testing a new blood test method (called Delta-HLD) to detect colorectal cancer or pre-cancerous growths. Researchers want to see if this non-invasive test can accurately identify cancer compared to traditional biopsy or surgery results. **You may be eligible if...** - You are scheduled to have a colonoscopy or colorectal surgery - You are willing and able to provide a blood and/or tissue sample before treatment **You may NOT be eligible if...** - You have a previous history of colorectal cancer - You have inflammatory bowel disease (such as Crohn's disease or ulcerative colitis) - You have a known hereditary cancer syndrome (such as Lynch syndrome or FAP) - You have another active cancer - You have recently received chemotherapy or immunosuppressive drugs Talk to your doctor to see if this trial is right for you.