RecruitingNCT07153458

Identification of New Non-invasive, Predictive, and Diagnostic Biomarkers for Colorectal Cancer

Sponsor

Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis

Enrollment

60 participants

Start Date

Dec 1, 2025

Study Type

OBSERVATIONAL

Conditions

CRC (Colorectal Cancer)Adenoma Colon

Summary

The study in question is an observational study that aims to identify new non-invasive biomarkers present in the serum of patients with CRC and, subsequently, to create a score capable of predicting the development of CRC. It is an observational study with 3 enrollment arms: Arm 1: Patients undergoing surgery at the U.O.C. of Surgery, with a CRC diagnosis; Arm 2: Subjects with a negative result from the endoscopic examination; Arm 3: Subjects in whom the presence of an adenoma with high-grade dysplasia is found, a condition considered pre-cancerous.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking for new non-invasive markers in blood or other body fluids that could help detect colorectal cancer (CRC) earlier or more accurately. Participants include people with colorectal cancer, people with pre-cancerous growths, and healthy individuals for comparison. **You may be eligible if...** - You are undergoing surgery for colorectal cancer (Aim 1), OR - You have no colon disease and are participating as a healthy comparison group (Aim 2), OR - You have a pre-cancerous polyp (adenoma with high-grade changes) in your colon (Aim 3) **You may NOT be eligible if...** - You have a condition not covered by the three groups above Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Biobank Core Facility

Castellana Grotte, Italy

View Full Details on ClinicalTrials.gov

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NCT07153458

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