RecruitingNCT07154823

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies


Sponsor

Tempus AI

Enrollment

550 participants

Start Date

Jan 27, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

The TEMPUS AQUARIUS Study is a non-interventional, longitudinal observational study focused on hematological malignancies. It will collect rich molecular (multi-omic) and clinical data from patient cohorts through serial blood draws and the acquisition of leftover tissue and/or bone marrow aspirates during their routine therapy and disease monitoring. The primary goal is to understand the association between biomarkers and real-world clinical outcomes in these patient populations.


Eligibility

Min Age: 0 Years

Plain Language Summary

Simplified for easier understanding

This registry study is collecting blood and tissue samples (biospecimens) from patients with certain blood cancers — including acute myeloid leukemia (AML) and follicular lymphoma — to discover new biological markers that can improve diagnosis and treatment decisions over time. **You may be eligible if...** - You are willing to participate and provide biological samples - You have a confirmed diagnosis of AML (any secondary AML is allowed), OR - You have confirmed follicular lymphoma and meet specific subgroup criteria based on your disease status (newly diagnosed, high-risk, relapsed, or transformed) **You may NOT be eligible if...** - You are unwilling or unable to follow study procedures - For AML: you have already received standard treatment for AML - For follicular lymphoma: you do not meet the specific subgroup criteria (e.g., you have been previously treated when the study requires treatment-naïve) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERNone - Observational Study

There are no interventions in this observational study.


Locations(5)

The Center for Cancer and Blood Disorders

Bethesda, Maryland, United States

Cancer Care Specialists of Reno

Reno, Nevada, United States

Taylor Cancer Research Center

Maumee, Ohio, United States

Cancer Care Associates of York

York, Pennsylvania, United States

Avera Cancer Institue

Sioux Falls, South Dakota, United States

View Full Details on ClinicalTrials.gov

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NCT07154823


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