RecruitingPhase 4NCT07158476

Efficacy of Methylprednisolone for Pain Control After ACL Repair

Efficacy of Methylprednisolone for Pain Control After ACL Repair: A Randomized Controlled Trial


Sponsor

St. Louis University

Enrollment

90 participants

Start Date

Oct 21, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repair surgery to determine if this results in decreased postoperative pain and opioid use without increasing complications.


Eligibility

Min Age: 13 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Gabapentin 300 mg, a drug called Hydrocodone 5Mg/Acetaminophen 325Mg Tab, and others for people with acl surgery and pain management. The study is currently recruiting participants at 1 location. People eligible for this study include aged 13 Years to 50 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMeloxicam 15 mg

PO once/day for 1 week

DRUGMedrol 4 MG Oral Tablet Includes Medrol Dosepak

PO 6 day taper

DRUGGabapentin 300 mg

PO every 8 hours for 1 week

DRUGHydrocodone 5Mg/Acetaminophen 325Mg Tab

PO 1-2 tabs every 4 hours as needed (total of 28 pills)

DRUGKetorolac 10 Mg Oral Tablet

PO every 6 hours for 5 days


Locations(1)

Saint Louis University

St Louis, Missouri, United States

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NCT07158476


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