Efficacy of Methylprednisolone for Pain Control After ACL Repair
Efficacy of Methylprednisolone for Pain Control After ACL Repair: A Randomized Controlled Trial
St. Louis University
90 participants
Oct 21, 2025
INTERVENTIONAL
Conditions
Summary
Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repair surgery to determine if this results in decreased postoperative pain and opioid use without increasing complications.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
PO once/day for 1 week
PO 6 day taper
PO every 8 hours for 1 week
PO 1-2 tabs every 4 hours as needed (total of 28 pills)
PO every 6 hours for 5 days
Locations(1)
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NCT07158476