RecruitingNot ApplicableNCT07158736

Genicular Nerve Block for Knee Pain in the ED

Ultrasound-Guided Genicular Nerve Block for Knee Pain in the Emergency Department: A Randomized Controlled Trial


Sponsor

University of Pennsylvania

Enrollment

34 participants

Start Date

Aug 6, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Genicular nerve block with bupivacaine and corticosteroids and Standard of Care for people with knee pain. The study is currently recruiting participants at 4 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREGenicular nerve block with bupivacaine and corticosteroids

genicular nerve block with ideal body-weight dosing of bupivacaine 0.5% with 4 mg dexamethasone

OTHERStandard of Care

This involves standard of care pain relief for patients who do not receive the genicular nerve block for knee pain, such as acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), and opioids.


Locations(4)

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Pennsylvania Hospital

Philadelphia, Pennsylvania, United States

Pennsylvania Presbyterian Medical Center

Philadelphia, Pennsylvania, United States

HUP Cedar

Philadelphia, Pennsylvania, United States

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NCT07158736


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