Repetitive Transcranial Magnetic Stimulation (rTMS) in MS Induced Spastic Paraparesis

This trial tests whether repetitive transcranial magnetic stimulation (rTMS) — a non-invasive brain stimulation technique using magnetic pulses — can reduce leg stiffness and spasticity in people with multiple sclerosis (MS). Spasticity in MS causes painful muscle tightness, mainly in the legs. **You may be eligible if...** - You are between 18 and 70 years old - You have been diagnosed with MS (by 2017 McDonald Criteria) - You have moderate to moderately severe disability with significant leg spasticity (EDSS 3.0–6.5, pyramidal score ≥3) - Your MS symptoms have been stable for at least 30 days with no recent relapses **You may NOT be eligible if...** - You have another neurological disorder adding to your disability - You have a significant heart condition, psychiatric illness, or severe lung disease - You recently changed your MS disease-modifying therapy (within 3 months) - You plan to start new spasticity medications during the study Talk to your doctor to see if this trial is right for you.