Letrozole Extended vs Traditional Therapy for Ovulation Induction in Women With PCOS (PROLEx-PCOS)

This trial compares two ways of using letrozole (a medication that stimulates egg release) to help women with Polycystic Ovary Syndrome (PCOS) get pregnant: the traditional shorter course vs. an extended course over more days. The goal is to find the most effective approach for triggering ovulation. **You may be eligible if...** - You are a woman between 18 and 40 years old - You have a confirmed diagnosis of PCOS - Your BMI is between 18.5 and 31 kg/m² - You are actively trying to become pregnant - Your weight has been stable and you have no major fertility-blocking conditions in your tubes or uterus **You may NOT be eligible if...** - You have blocked fallopian tubes or severe male-factor infertility - You have premature ovarian failure or uncontrolled thyroid/prolactin problems - You have a history of gynecologic or breast cancer - You have a known allergy to letrozole - You are currently pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.