RecruitingNot ApplicableNCT07161713

SBU-RESET: RElaxation, Stress Reduction and Epigenetics Trial in Cancer Survivors

Pilot Study of a Social/Behavioral Intervention on Lung, Colon, and Non-Hodgkin's Lymphoma (NHL) Cancer Survivors, Evaluating the Effect of Mind Body Interventions on Patient Reported Outcomes, Inflammation and Epigenetics.

Sponsor

Barbara Nemesure

Enrollment

100 participants

Start Date

Sep 17, 2025

Study Type

INTERVENTIONAL

Conditions

Colon Cancer Lung Cancer (Diagnosis)Lung Adenocarcinoma Lung Adenocarcinoma Stage III Lung Adenocarcinoma Stage IV Lung Adenocarcinoma Metastatic Lung Adenocarcinoma Stage IIIB/IV Lung Adenocarcinoma Stage I Lung Adenocarcinoma Stage II NHL NHL - Non-Hodgkin&Amp;#39;s Lymphoma

Summary

Cancer survivors can experience health issues that cause chronic illness and lower quality of life. Yoga is a well-known holistic approach to health and overall well-being. Mindfulness has many benefits, including improved focus and less stress. This study aims to evaluate if yoga and/or mindfulness has a positive effect on cancer survivors social, emotional and physical well-being as well as their epigenetics. Epigenetics is how the environment can effect your genes; not by changing our DNA, but by turning genes on or off.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study explores whether a stress reduction and relaxation program can cause positive changes in the biological markers (epigenetic changes) of cancer survivors. Researchers want to see if calming interventions affect how genes are expressed in people who have had lung cancer, colon cancer, or non-Hodgkin's lymphoma. **You may be eligible if...** - You are 18 or older - You have been diagnosed with lung cancer, colon cancer, or non-Hodgkin's lymphoma - It has been at least 6 months since you finished chemotherapy, targeted therapy, or immunotherapy - You are able to provide a saliva sample - You can complete questionnaires in English **You may NOT be eligible if...** - You have primary anal or rectal cancer - You are currently receiving active cancer treatment - You have a condition that prevents you from producing saliva - You are unable to commit to the full study period and follow-up Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALOncology-informed yoga

8 weekly sessions of cancer informed-yoga incorporating light movement, breathing techniques, and some meditation practices

BEHAVIORALSMART

SMART, developed by the Impact Foundation, is an adaptation of Mindfulness-based Stress Reduction (MBSR) approach that incorporates other elements like mindful self-compassion, emotional literacy, and positive psychology principles to address the unique stressors faced by teachers.