RecruitingNot ApplicableNCT07162337

BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention

BILMOD: BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention


Sponsor

Massachusetts General Hospital

Enrollment

40 participants

Start Date

Jun 18, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This research study is a prospective, single-arm clinical trial to assess the effect of a dietary intervention for more plant-based and less animal-based food intake on secondary bile acid production, gut microbiota, circulating biomarkers and gene expression associated with colonic bile acid receptor activation and colorectal cancer.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Increased Plant-Based Diet and Decreased Animal-Based Diet for people with colorectal adenoma and colorectal cancer prevention. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALIncreased Plant-Based Diet and Decreased Animal-Based Diet

Self-regulated diet; increased plant-based foods with decreased animal-based foods


Locations(1)

Massachusetts General Hospital Cancer Center

Boston, Massachusetts, United States

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NCT07162337


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