The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail
Impact of Whey Protein on Frailty - a Pilot Study
University of Kansas Medical Center
20 participants
Oct 1, 2025
INTERVENTIONAL
Conditions
Summary
This pilot study aims to determine the impact of whey protein supplementation on brain antioxidant levels and to assess the effects of whey protein supplementation on physical function, body composition, and cognition in pre-frail older adults.
Eligibility
Inclusion Criteria5
- Pre-frail according to Fried's phenotype
- Age 65 to 85
- Speak English as primary language and able to read and write in English
- Stable medication for ≥ 30 days
- Not already taking whey protein over the past 30 days
Exclusion Criteria11
- Acute or chronic kidney disease
- Recent major health concerns
- Insulin-requiring diabetes
- Cancer requiring chemotherapy or radiation within the past 5 years
- Cardiac event (i.e., MI, etc.) in the past year
- Dementia or neurodegenerative disease
- Clinical trial or investigational drug or therapy participation within 30 days of the screening visit or during enrollment in the current study
- MRI contraindications (pacemaker, aneurysm clips, artificial heart valves, metal fragments, foreign objects or claustrophobia)
- Dairy Allergy or excluding dairy from diet for other reasons
- Weight \> 350 lbs.
- The presence of major psychiatric disorders within the past 3 years including depression, anxiety, and alcohol (over 3 drinks/day or a total of 18 drinks/week) or drug abuse.
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Interventions
24g of whey protein will be given to the participant to be consumed daily. Participants will be asked to consume 1 serving per day for 3 months.
A calorie matched serving of carbohydrate powder will be given to participants to consume daily. Participants will be asked to consume 1 serving per day for 3 months.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07167277