Physical Function Clinical Trials

18 recruitingLast updated: June 18, 2026

There are 18 actively recruiting physical function clinical trials across 8 countries. Studies span Not Applicable, Phase 2. Top locations include Boston, Massachusetts, United States, Barakaldo, Vizcaya, Spain, Aurora, Colorado, United States. Updated daily from ClinicalTrials.gov.


Physical Function Trials at a Glance

18 actively recruiting trials for physical function are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 15 trials, with the heaviest enrollment activity in Boston, Barakaldo, and Aurora. Lead sponsors running physical function studies include Massachusetts General Hospital, Istinye University, and Foundation University Islamabad.

Browse physical function trials by phase

Treatments under study

About Physical Function Clinical Trials

Looking for clinical trials for Physical Function? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Physical Function trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Physical Function clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 118 of 18 trials

Recruiting
Phase 2

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

FrailtyAgingHIV-1-infection+2 more
Massachusetts General Hospital100 enrolled2 locationsNCT06554717
Recruiting
Not Applicable

Frame Running for Exercise and Participation for Children and Young People With Physical Disabilities

Quality of LifePhysical ActivityPhysical Function+2 more
Odense University Hospital35 enrolled1 locationNCT07543614
Recruiting
Not Applicable

IMST for Dementia Risk Reduction

Sleep QualityCognitive FunctionBlood Pressure+4 more
Florida State University30 enrolled1 locationNCT07349706
Recruiting
Not Applicable

Function and Lean Mass Preservation With Resistance Exercise During a GLP-1RA Treatment

Obesity, OverweightPhysical FunctionMuscle Mass and Strength
University of Exeter60 enrolled1 locationNCT07457437
Recruiting
Not Applicable

A Digital Health Intervention to Improve Physical Function and Wellness of Lung Cancer Survivors

Advanced Lung CancerPhysical Function
Massachusetts General Hospital250 enrolled1 locationNCT07227623
Recruiting
Not Applicable

Group Recreation to Enhance Function Aging

Physical functioningCognitive functioning
State University of New York at Buffalo80 enrolled1 locationNCT07050589
Recruiting
Not Applicable

Therapeutic Effects of Instrument-assisted Versus Sound-assisted Soft Tissue Mobilization in Chronic Non-specific Low Back Pain

Chronic non-specific low back painDisabilityPhysical Function+3 more
University of Lahore60 enrolled2 locationsNCT07244913
Recruiting

Outdoor Horseback Riding and Its Effects on Muscle Strength, Balance, Sleep, and Movement

Physical Functional PerformanceSports Physical TherapyHorseback Riding
Istinye University64 enrolled3 locationsNCT07286864
Recruiting
Not Applicable

The Effects of MediDrink Platinum+ and Fava Bean Protein Hydrolysate on Fitness in an Aged Population

Physical FunctionSarcopenia in ElderlyStrength+3 more
Nuritas Ltd75 enrolled2 locationsNCT07322653
Recruiting
Not Applicable

PREPARE: Perioperative REhabilitation Around Vaginal Prolapse RepAir Surgery for Recovery Enhancement

Postoperative Physical Functioning
University of New Mexico92 enrolled1 locationNCT07265973
Recruiting
Not Applicable

The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail

MRIPhysical FunctionCognition+3 more
University of Kansas Medical Center20 enrolled1 locationNCT07167277
Recruiting
Not Applicable

Prehabilitation for Colorectal Cancer Patients With Low Functional Capacity and Malnutrition

PrehabilitationMalnutritionPhysical Functional Performance
McGill University60 enrolled1 locationNCT05999370
Recruiting
Not Applicable

Building Resilience for Surgical Recovery

SurgeryOlder AdultsDepressive Symptoms+3 more
The University of Texas Health Science Center, Houston90 enrolled1 locationNCT06174701
Recruiting
Not Applicable

Church-based Intervention to Improve Physical Function

Physical FunctionMultiple Chronic Conditions
Rush University Medical Center360 enrolled1 locationNCT05345041
Recruiting
Not Applicable

Action Observation Training for Functional Performance in Children with Cerebral Palsy

Physical Functional PerformanceCerebral Palsy (CP)
Foundation University Islamabad30 enrolled1 locationNCT06672328
Recruiting

Movement and Behaviours Measurement Study

Frailty SyndromeAgingPhysical Function+2 more
University of Castilla-La Mancha90 enrolled1 locationNCT04173715
Recruiting
Not Applicable

Face-to-face vs Online Physical Exercise in Seniors Living in Nursing Homes (ExerMOT-NH)

Cognitive DeclinePhysical Function
University of the Basque Country (UPV/EHU)120 enrolled4 locationsNCT06352749
Recruiting
Not Applicable

Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms

ExerciseBody CompositionSarcopenia+15 more
University of Copenhagen144 enrolled1 locationNCT05307367