ClinicalTrialsFinder
RecruitingNot ApplicableNCT07171658

Breast Cancer-Related Approach for Increasing Cervical Cancer Screening

Improving Cervical Cancer Screening Coverage Among Underscreened Women Aged 50 to 74 in Switzerland Using HPV Self-sampling Strategies: A Randomized Study - Breast Cancer-Related Approach for Increasing Cervical Cancer Screening

Sponsor

Jessica Di Vincenzo Sormani

Enrollment

4,500 participants

Start Date

Oct 7, 2025

Study Type

INTERVENTIONAL

Conditions

Cervical Cancer Screening

Summary

The primary objective of this clinical trial is to assess cervical cancer screening participation among under-screened women invited through organized breast cancer screening programs in Switzerland. This randomized trial will compare three arms: 1. Intervention group 1: Sensitization to Cervical Cancer (CC) screening Women will receive an awareness letter explaining the importance of cervical cancer screening, the Swiss recommendations and an invitation to schedule an appointment. 2. Intervention group 2: Home-based Human papillomavirus infection (HPV) self-sampling Women will receive a free-of-charge vaginal self-sampling kit for HPV infection 3. Observational control group Women selected in the control arm will only be recruited one year following the screening of those in the intervention arm (T0+1), as to not influence Cervical Cancer Screening (CCS) behavior during this period by being reminded of screening recommendations.

Eligibility

Sex: FEMALEMin Age: 50 YearsMax Age: 74 Years

Inclusion Criteria4

  • Women receiving Breast Cancer Screening (BCS) invitation letters in the selected five cantons (Geneva, Bern (francophone), Jura, Neuchâtel, and Vaud)
  • Aged 50 to 74 years old
  • Not been screened for cervical cancer in the past three years
  • Speaking one of the 6 languages of the study (French, German, Italian, and in English, Spanish, and Portuguese)

Exclusion Criteria5

  • Prior cervical cancer diagnosis,
  • Hysterectomy
  • Non consent to participate to the study
  • Incapable of judgment or under tutelage
  • Pregnancy

Interventions

BEHAVIORALSensitization to Cervical Cancer (CC) screening

Women will receive an awareness letter explaining the importance of cervical cancer screening, the Swiss recommendations and an invitation to schedule an appointment.

BEHAVIORALHome-based HPV self-sampling

Women will receive a free-of-charge vaginal self-sampling kit for HPV infection.

Locations(1)

University Hospitals of Geneva

Geneva, Canton of Geneva, Switzerland

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07171658