RecruitingNot ApplicableNCT07173205

Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit

R00 Full Factorial Trial: Optimizing ASCENT


Sponsor

East Carolina University

Enrollment

208 participants

Start Date

Oct 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Our team has developed a digital intervention that aims to help adolescent and young adult cancer survivors (AYAs) manage symptoms of depression. This tool includes one psychoeducation component and four components that are based on evidence-based interventions for depression. The goal of this study is to test which component or combination of components meaningfully contribute to improvements in depressive symptoms among AYAs.


Eligibility

Min Age: 15 YearsMax Age: 39 Years

Plain Language Summary

Simplified for easier understanding

This study is refining and testing a digital toolkit called ASCENT designed to help adolescents and young adults (AYAs) who have completed cancer treatment cope with emotional challenges, stress, and life after cancer. Participants will help shape and improve the app. **You may be eligible if...** - You are between 15 and 39 years old - You were diagnosed with cancer between ages 12 and 39 - You finished cancer treatment between 1 month and 5 years ago - You speak and read English fluently - You own a smartphone with a data plan **You may NOT be eligible if...** - You have a severe or persistent mental illness - You currently have severe suicidal thoughts with a plan and intent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALAYA Survivors Coping and Emotional Needs Toolkit (ASCENT)

Participants will receive access to a digital depression self-management tool (ASCENT), which aims to help AYAs manage symptoms of depression post-treatment. All users will have access to the core tool which includes daily mood tracking and a psychoeducational module about cancer and depression. Depending on assigned condition, participants will also receive access to up to 4 intervention modules which have been adapted from existing evidence-based treatments for digital delivery to AYAs through a rigorous user-centered design process. Within each module there are 6 micro-lessons that include an educational video, a real story from an AYA that demonstrates the topic, multiple choice questions that ask the participant to apply the educational information to the AYA story, open-ended questions that ask the participant to apply the educational information to their own experience, and a practice activity in which they are asked to try out a relevant skill.


Locations(2)

East Carolina University

Greenville, North Carolina, United States

Wake Forest University

Winston-Salem, North Carolina, United States

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NCT07173205


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