RecruitingNot ApplicableNCT07175376

Resilience Enhancement Using Electronic Frailty Index-Directed Care Pathway

Resilience Enhancement Utilizing an Electronic Frailty Index-Directed Care Pathway for Older Adults Receiving Chemotherapy (RESILIENCE-e): A Prospective Single-Arm Interventional Study


Sponsor

Wake Forest University Health Sciences

Enrollment

32 participants

Start Date

Mar 16, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The study purpose is to gain a better understanding of the needs of adults aged 65 and older while they are receiving chemotherapy by measuring their resilience and tailor care plans based on their individual needs.


Eligibility

Min Age: 65 Years

Inclusion Criteria8

  • Patients with cancer:
  • Ability to understand and willingness to sign an IRB-approved informed consent
  • Age ≥ 65 years at the time of enrollment.
  • Planned to initiate an outpatient chemotherapy regimen for cancer treatment (any type or stage), either as an initial therapy or as a new line of therapy, with curative or palliative intent.
  • eFI pre-frail or frail status (available in EHR) within 30 days before enrollment.
  • Ability to read and understand the English language
  • Providers:
  • Treating medical oncologist of at least one patient participant who enrolled on to the study and completed baseline assessment.

Exclusion Criteria4

  • Patients:
  • Documented physical or psychological comorbidity that would limit participant's ability to understand or comply with study procedures for the entire length of the study per the enrolling investigator.
  • Chemotherapy planned at a facility outside the Atrium Health system.
  • Currently receiving chemotherapy

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Interventions

OTHERSupportive Care

Geriatric assessment (GA) -guided supportive care and weekly Patient Reported Outcomes (PRO) symptom assessment


Locations(2)

Levine Cancer Institute

Charlotte, North Carolina, United States

Atrium Health Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina, United States

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NCT07175376


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