Frail Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Frail clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 40 trials

Recruiting
Not Applicable

Optimised Post-discharge Care in Older Patients After Surgery for Colon Cancer (ERAS 3.0)

Colon CancerFrailty
Copenhagen University Hospital at Herlev60 enrolled2 locationsNCT06802991
Recruiting

Evaluation of the Impact of Interventional Treatments for Symptomatic, Severe Tricuspid Valve Insufficiency on Renal Integrity and Function, as Well as on Physical Function and Activity in Older Adults.

FrailtyTricuspid RegurgitationCardio-Renal Syndrome+1 more
Robert Bosch Medical Center100 enrolled1 locationNCT07464106
Recruiting

Visual Frailty in Ageing

Cognitive ImpairmentDepressionAnxiety+5 more
University of Edinburgh20 enrolled2 locationsNCT06604104
Recruiting
Phase 2

Improving Physical Ability and Cellular Senescence Elimination in HIV

FrailtyHIVAging Problems+1 more
National Institute of Allergy and Infectious Diseases (NIAID)80 enrolled27 locationsNCT07144293
Recruiting

Individualized Dynamic Frailty-tailored Therapy (DynaFiT) in Elderly Patients With NDMM

Multiple MyelomaFrailty
FengYan Jin131 enrolled1 locationNCT06099912
Recruiting

Physical Performance Assessment in Kidney Transplant Evaluation

Frailty Syndrome
University Hospital, Martin50 enrolled1 locationNCT07338929
Recruiting

Taining Golden Lake Comprehensive Chronic Disease Management Initiative

SarcopeniaDiabetes MellitusHypertension+4 more
First Affiliated Hospital of Fujian Medical University20,000 enrolled1 locationNCT07308314
Recruiting
Not Applicable

ICOPE Program Feasibility in the Management of Myeloma Patients

Multiple MyelomaFrailty
University Hospital, Toulouse30 enrolled1 locationNCT06247189
Recruiting

Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

HypertensionStrokeInfections+5 more
International Consortium of Circulatory Assist Clinicians150 enrolled7 locationsNCT06039176
Recruiting
Not Applicable

Virtual Home-based Physical Pre-habilitation in Kidney Transplant Candidates

FrailtyTransplant;Failure,KidneyKidney Disease, End-Stage
McGill University Health Centre/Research Institute of the McGill University Health Centre30 enrolled2 locationsNCT06089473
Recruiting

Predictors of Emergency Department Use in Frail Patients

ElderlyFrailtyAlzheimer s Disease+3 more
University of Pisa110 enrolled1 locationNCT07259499
Recruiting
Not Applicable

A High Protein Egg White Pudding for People With Kidney Failure (HiPE KF)

Kidney Disease, ChronicFrailtyKidney Failure
Seven Oaks Hospital Chronic Disease Innovation Centre54 enrolled2 locationsNCT06343727
Recruiting

The Better, Harder, Faster, Stronger Study

Ovarian CancerEndometrial CancerNeoadjuvant Chemotherapy+2 more
Wake Forest University Health Sciences35 enrolled1 locationNCT07220512
Recruiting
Not Applicable

The Impact of Geriatric Assessment on the Treatment Plan of Elderly Patients With T2DM

Geriatric AssessmentFrailtyType2diabetes+1 more
Hospital de Clinicas de Porto Alegre220 enrolled1 locationNCT06469437
Recruiting

Association of POCD With Circulating Biomarkers in Patients Undergoing TUR of Bladder Tumor

Cognitive DeclineUrinary Bladder CancerGeneral Anesthesia+8 more
Osijek University Hospital42 enrolled1 locationNCT07165236
Recruiting
Not Applicable

Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.

Pain, ChronicKidney DiseasesFrailty+1 more
University of Illinois at Chicago150 enrolled1 locationNCT06374537
Recruiting
Not Applicable

Personalized Health Coaching for Patients With HF

Heart FailureRandomized Controlled TrialFrailty+3 more
Gachon University Gil Medical Center80 enrolled1 locationNCT07111585
Recruiting

Influence of Frailty on Cardiovascular Events and Mortality in Patients With COPD.

Role of Frailty in COPD
Azienda Ospedaliero-Universitaria di Modena300 enrolled1 locationNCT05922202
Recruiting
Not Applicable

Prehabilitation in Pancreatic Surgery

Pancreatic CancerFrailty SyndromePerioperative/Postoperative Complications+2 more
IRCCS San Raffaele238 enrolled1 locationNCT06069297
Recruiting
Phase 2

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

FrailtyAgingHIV-1-infection+2 more
Massachusetts General Hospital100 enrolled2 locationsNCT06554717