RecruitingNot ApplicableNCT07181096

Frailty Among Renal Transplant Recipients and Relation to Chronic Allograft Dysfunction

Study of Frailty Among Renal Transplant Recipients, Its Relation to Chronic Renal Allograft Dysfunction

Sponsor

Alexandria University

Enrollment

80 participants

Start Date

Jul 15, 2025

Study Type

INTERVENTIONAL

Conditions

Renal transplant Frailty

Summary

The aim of the study is to assess prevalence of frailty among renal transplant recipients in Alexandria University Hospitals and to study the relation between frailty and chronic allograft dysfunction.

Eligibility

Min Age: 18 Years

Inclusion Criteria1

Renal transplanted patients with GFR more than 30

Exclusion Criteria5

Mentally or physically unfit patients.
Amputation of lower limb.
Active neoplasia, chronic liver disease, previous immunological disease.
Psychiatric disorders.
Pregnancy.

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Interventions

DIAGNOSTIC_TESTassessment of frailty

This study is a prospective cross-sectional study to assess the prevalence of frailty among 80 cases of renal transplanted patients. Specific tests will include: 1. Assessment of frailty by Clinical Frailty Scale. 2. Assessment of nutritional status using Patient Generated Subjective Global Assessment (PG-SGA). 3. Comorbidity assessment using Charlson comorbidity score. 4. Six minutes walk test. 5. Muscle strength assessment using hand grip strength (HGS) dynamometer.