RecruitingNot ApplicableNCT07183683

Stimulation of Acupuncture Points in Female Patients With Multiple Sclerosis and Neurogenic Bladder Dysfunction

Electrical Versus Manual Stimulation of Acupuncture Points in Female Patients With Multiple Sclerosis and Neurogenic Bladder Dysfunction - A Pragmatic, Exploratory, Three-Arm, Randomized Controlled Trial Using a Mixed Methods Approach


Sponsor

Charite University, Berlin, Germany

Enrollment

150 participants

Start Date

Sep 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Electrical vs. manual stimulation: The study compares two types of acupuncture - one using mild electrical currents and one using just manual no-needle techniques in the treatment of urinary bladder disfunction. The study focuses on women diagnosed with multiple sclerosis (MS) who also have neurogenic bladder dysfunction - a condition where the bladder doesn't work properly due to nerve damage.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether acupuncture can help women with multiple sclerosis (MS) who have bladder control problems, such as sudden urges to urinate, frequent urination, or leaking. **You may be eligible if...** - You are a woman aged 18–60 with relapsing-remitting MS - You have been on stable MS medication for at least 3 months - You have at least 3 bladder symptoms like urgency, frequent daytime urination, nighttime urination, or leaking **You may NOT be eligible if...** - You had an MS relapse in the past 3 months - You regularly need to use a catheter (more than twice a week) - You have a history of bladder cancer, a pacemaker, or defibrillator - You have had pelvic, spinal, or bladder surgery, or a spinal injury in the past 5 years - You have had a urinary tract infection in the past 4 weeks - You are pregnant or breastfeeding - Your BMI is over 30 Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEgroup 1: electrical stimulation of acupuncture points plus routine care

The acupuncture points Spleen 6 and Kidney 3 will be stimulated twice daily with a up to 30min electrical stimulation per foot with 10Hz and an intensity up to individual tolerance level.

OTHERgroup 2: acupressure plus routine care

The acupuncture points Spleen 6 and Kidney 3 will be stimulated twice daily with a up to 30min massage per foot


Locations(1)

Department for integrative medicine and prevention, Institute for social medicine, epidemiology and health economics, Charité university medicine Berlin

Berlin, State of Berlin, Germany

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NCT07183683


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