RecruitingNCT07183891

Performance of Large Language Models for Structured Recognition and Refractive Prediction

Head-to-Head Evaluation of ChatGPT 4o, GPT-5, and DeepSeek for Structured Extraction, Toric IOL Recommendation, and Refractive Prediction


Sponsor

Jin Yang

Enrollment

100 participants

Start Date

Aug 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

We conducted a single-center, retrospective observational study to evaluate large language models (ChatGPT 4o, GPT-5, DeepSeek) for automated interpretation of de-identified IOLMaster 700 reports provided as raster images. Models produced structured biometric extraction, toric IOL recommendation, and refractive predictions (sphere, cylinder, axis). Primary outcomes included parameter-level agreement and refractive error metrics; secondary outcomes included decision-support performance for toric IOL selection and agreement on ordered T-codes. No clinical intervention was performed.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with cataract. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Eye and ENT hospital of Fudan University

Shanghai, Shanghai Municipality, China

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NCT07183891


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