RecruitingNot ApplicableNCT07196436

Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study

Energy Recovery Ventilation and Air Cleaner Interventions to Improve Indoor Air Quality, Mold Control, and Asthma-Related Health Outcomes Among Inner-City Children and Adults in Low-Income Households


Sponsor

The University of Texas at Arlington

Enrollment

80 participants

Start Date

Oct 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The primary goal of this study is to investigate the comparative long-term (i.e., 1-year) effectiveness of energy recovery ventilators (ERVs) and portable air cleaners (PACs) in reducing indoor air pollutants and mold levels and improving asthma-related health outcomes in inner-city children and adults with asthma in low-income households in the Dallas-Fort Worth (DFW) metropolitan area, TX. Secondary goals include: (1) examining associations among asthma outcomes, exposure to indoor air pollutants and mold, and housing-related factors, (2) conducting a cost-benefit analysis of ERV and PAC interventions for improving IAQ, mold control, and health outcomes, and (3) evaluating the utility of cost-effective methods and protocols for measuring IAQ and mold for indoor air pollution epidemiology studies and for providing practical information to patients and their physicians. Using a double-blind, placebo-controlled randomized controlled trial, 80 households will be assigned to receive active or placebo versions of ERVs or PACs. Environmental exposures and housing conditions will be monitored alongside comprehensive health assessments, including lung function tests and validated surveys on asthma control, quality of life, stress, and sleep quality.


Eligibility

Min Age: 5 Years

Plain Language Summary

Simplified for easier understanding

This trial (AIRVAC) is testing whether installing home ventilation systems and portable air cleaners in the homes of people with asthma reduces symptoms and improves asthma control, by reducing exposure to indoor air pollutants and allergens. **You may be eligible if...** - You or your child (aged 5–17) have been diagnosed with asthma by a physician - You own your home and live in the Dallas–Fort Worth (DFW) metropolitan area in Texas **You may NOT be eligible if...** - Anyone living in your home is a smoker Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICEEnergy Recovery Ventilator

A mechanical ventilation system that exchanges stale indoor air with fresh outdoor air while transferring heat and moisture between the incoming and outgoing air streams

DEVICEPortable Air Cleaner

A standalone home device that filters indoor air to remove particulate matter, allergens, and other pollutants

DEVICEEnergy Recovery Ventilator (Sham)

A home-installed ERV unit that operates in recirculation mode only, providing no fresh air exchange or heat/moisture transfer, serving as a placebo for study purposes.

DEVICEPortable Air Cleaner (Sham)

A portable air cleaner that appears to operate like an active unit but does not contain a HEPA filter and does not clean the air, serving as a placebo for study purposes


Locations(2)

University of Texas at Arlington

Arlington, Texas, United States

Rebuilding Together North Texas

Plano, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07196436


Related Trials