Stress Clinical Trials

1,166 recruitingLast updated: June 9, 2026

There are 1,166 actively recruiting stress clinical trials across 76 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1, Early Phase 1. Top locations include Boston, Massachusetts, United States, New York, New York, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Stress Trials at a Glance

1,166 actively recruiting trials for stress are listed on ClinicalTrialsFinder across 6 cities in 76 countries. The largest study group is Not Applicable with 715 trials, with the heaviest enrollment activity in Boston, New York, and Houston. Lead sponsors running stress studies include VA Office of Research and Development, Massachusetts General Hospital, and Karolinska Institutet.

Treatments under study

About Stress Clinical Trials

Looking for clinical trials for Stress? There are currently 322 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Stress trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Stress clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,166 trials

Recruiting

Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry

pelvic organ prolapseStress Urinary Incontinence
Ethicon, Inc.1,000 enrolled10 locationsNCT04829175
Recruiting
Not Applicable

Targeted Plasticity Therapy for PTSD

PTSD - Post Traumatic Stress Disorder
The University of Texas at Dallas20 enrolled3 locationsNCT06266364
Recruiting
Not Applicable

Impact of Heat on Dual Task Performance

HealthyHeat Stress, Exertional
Louisiana State University Health Sciences Center Shreveport10 enrolled1 locationNCT07629414
Recruiting
Not Applicable

TAG TEAM - Trans Adolescent Group Therapy

CopingPsychological DistressAnxiety+7 more
Murdoch Childrens Research Institute142 enrolled1 locationNCT07151079
Recruiting

Predictability of the Clinical Global Impression Scale (CGI) in Post Immediate in Psychotraumatic Impact

Post Traumatic Stress Disorder
Centre Hospitalier Arras241 enrolled5 locationsNCT05358067
Recruiting
Not Applicable

The Effect of Pre-Breastfeeding Breathing Exercises on Maternal Anxiety, Well-being, and Infant Stress in Mothers Whose Infants Are in the Neonatal Intensive Care Unit

StressAnxietyPsychological Well-being+2 more
Inonu University70 enrolled1 locationNCT07634445
Recruiting
Not Applicable

Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women

ObesityHypertensionDiabetes+4 more
Emory University269 enrolled1 locationNCT07111026
Recruiting
Not Applicable

ERP to Improve Functioning in Veterans With OCD

Obsessive Compulsive Disorder (OCD)Comorbid Post-Traumatic Stress Disorder and OCD
VA Office of Research and Development160 enrolled19 locationsNCT05240924
Recruiting

Post Market Clinical Follow-up Study on TVT ABBREVO® Continence System

Stress Urinary Incontinence
Ethicon, Inc.195 enrolled4 locationsNCT04829357
Recruiting
Not Applicable

Manage Emotions to Reduce Aggression (MERA)

Stress Disorders, Post-TraumaticAggressionEmotion Regulation
VA Office of Research and Development204 enrolled2 locationsNCT04793776
Recruiting
Not Applicable

Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence

Mixed urinary incontinenceUrinary IncontinenceStress Urinary Incontinence
NICHD Pelvic Floor Disorders Network358 enrolled7 locationsNCT06480227
Recruiting
Phase 2Phase 3

Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome

Mechanical Ventilation ComplicationAcute Respiratory Distress SyndromeSedation Complication
Guy's and St Thomas' NHS Foundation Trust20 enrolled1 locationNCT06014138
Recruiting
Phase 3

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

Urinary Incontinence, Stress
Eli Lilly and Company1,000 enrolled137 locationsNCT07202884
Recruiting
Phase 1

Pharmacokinetics and Placental Transfer of Caffeine

Apnea of PrematurityPremature BirthBronchopulmonary Dysplasia+2 more
Indiana University30 enrolled1 locationNCT07570121
Recruiting
Not Applicable

Mobile Intervention for Mental Health of Family Caregivers in Thailand

Depressive Symptoms, Generalized Anxiety, or Psychological Stress
Brigham and Women's Hospital400 enrolled1 locationNCT06722287
Recruiting
Not Applicable

Preventive Narrative Exposure Intervention for PTSD in ICU Patients After Cardiopulmonary Bypass Cardiac Surgery

Stress Disorders, Post-TraumaticCardiopulmonary BypassIntensive Care Units
First Affiliated Hospital of Fujian Medical University100 enrolled1 locationNCT07632131
Recruiting
Not Applicable

Achieving Routine Intervention and Screening for Emotional Health

Type 2 Diabetes Mellitus (T2DM)Diabetes Distress
University of Chicago1,250 enrolled1 locationNCT06887049
Recruiting
Phase 2

Department of Defense PTSD Adaptive Platform Trial - Master Protocol

Post Traumatic Stress Disorder
Global Coalition for Adaptive Research800 enrolled9 locationsNCT05422612
Recruiting
Not Applicable

Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery

Post Traumatic Stress Disorder (PTSD)Opioid-use DisorderIntimate Partner Violence (IPV)
Yale University532 enrolled3 locationsNCT07115030
Recruiting
Not Applicable

tAN for First Responders

Mental StressMental Fatigue
Spark Biomedical, Inc.30 enrolled1 locationNCT07109349