RecruitingPhase 3NCT07199894

Omegapres Versus Solifenacin and Mirabegron Combination Therapy in Treatment of Primary MNE

A Randomized Controlled Trial Comparing Mirabegron and Solifenacin Combination Therapy Versus Desmopressin Monotherapy in Treatment of Children With Primary Mono-Symptomatic Nocturnal Enuresis


Sponsor

Mansoura University

Enrollment

120 participants

Start Date

Dec 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare combination of Solifenacin and MIrabegron in treatment of primary mono-symptomatic nocturnal enuresis in children. It will also learn about the safety of that combination. The main questions it aims to answer are: Does combination of Solifenacin and MIrabegron lower the number of wet nights? What medical problems do participants have when taking combination of Solifenacin and MIrabegron? Researchers will compare the combination to omegapress to see if the combination works better to treat primary mono-symptomatic nocturnal enuresis. Participants will: Take the combination or Omegapress every day for 3 months Visit the clinic once monthly for checkups and tests Keep a diary of their symptoms and the number of wet nights


Eligibility

Min Age: 6 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Desmopressin (DDAVP) and a drug called Mirabegron (beta3-adrenoceptor agonist), Anticholinergics for people with nocturnal enuresis in children. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGMirabegron (beta3-adrenoceptor agonist), Anticholinergics

Anticholinergic and B3 agonist drugs used for treatment of mono-symptomatic nocturnal enuresis

DRUGDesmopressin (DDAVP)

ADH analogue in treatment of mono-symptomatic nocturnal enuresis


Locations(1)

Urology and Nephrology center - Mansoura University

Al Mansurah, Egypt

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07199894


Related Trials