Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

This study is comparing two different muscle relaxant medications used during surgery — rocuronium and cisatracurium — in patients with chronic kidney disease. Researchers want to find out which medication is safer and causes fewer complications in people with reduced kidney function. **You may be eligible if...** - You are between 18 and 80 years old - You have been diagnosed with chronic kidney disease (based on kidney filtration rate tests) - You are scheduled for surgery that requires general anesthesia with a breathing tube and muscle relaxants **You may NOT be eligible if...** - You are younger than 18 or older than 80 - You have end-stage kidney disease or are on dialysis - You are scheduled for a kidney transplant - You are pregnant - Your surgery is urgent or an emergency - Your surgery will require you to remain on a breathing tube after the operation - You have a known allergy to rocuronium, sugammadex, cisatracurium, or neostigmine - You are currently incarcerated Talk to your doctor to see if this trial is right for you.