RecruitingNCT07205523

High-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT)

High-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT): A Prospective Real-World Cohort Study in the Qinghai-Tibet Plateau


Sponsor

Yigeng Cao,MD,PhD

Enrollment

1,000 participants

Start Date

Sep 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The High-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT) study is the first prospective real-world cohort of hematologic diseases and transplantation in the Qinghai-Tibet Plateau. Patients undergoing hematopoietic stem cell transplantation (HSCT) at Qinghai University Affiliated Hospital, together with their donors, are systematically enrolled. The registry collects demographic, diagnostic, treatment, prognosis, and medical expense information, as well as biospecimens for future analyses. Historical data are incorporated, and prospective data collection is ongoing with long-term follow-up planned. The registry is designed as a sustainable research infrastructure to provide comprehensive data on disease incidence, treatment patterns, outcomes, and resource utilization in a high-altitude setting.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is observing how patients with blood diseases respond to stem cell transplantation (bone marrow transplant) when the procedure is performed at high altitude — specifically at a hospital in Qinghai, China, which sits at significant elevation. Researchers want to understand if high altitude affects recovery, blood counts, and outcomes after transplant. **You may be eligible if...** - You have been diagnosed with a blood disease requiring a stem cell transplant - You were admitted to the transplant center at Qinghai University Affiliated Hospital on or after September 1, 2023 - You are undergoing or have undergone a stem cell transplant - You have signed informed consent **You may NOT be eligible if...** - You have severe other illnesses or logistical circumstances that make long-term follow-up impossible - You have substance abuse issues that would interfere with study participation - The investigators judge that participating would put you at risk or compromise your safety or compliance Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Affiliated Hospital of Qinghai University

Xining, Qinghai, China

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NCT07205523


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