RecruitingNot ApplicableNCT07209176

Physician- and Patient-based Barriers to NGS Testing

A Clinical Trial to Address Physician- and Patient-based Barriers to NGS Testing

Sponsor

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Enrollment

256 participants

Start Date

Jan 6, 2026

Study Type

INTERVENTIONAL

Conditions

Metastatic Prostate Cancer

Summary

The goal of this study is to improve next-generation sequencing (NGS) testing rates at Johns Hopkins in patients with metastatic prostate cancer. Investigators believe by targeting two barriers, provider-level and patient-level, will improve the testing rate of NGS at Johns Hopkins.

Eligibility

Sex: MALEMin Age: 18 Years

Inclusion Criteria2

men diagnosed with metastatic prostate cancer
seen by Johns Hopkins Medical Oncology as a new patient visit between January 1, 2025 and December 31, 2026

Exclusion Criteria1

\- Patients who have already had NGS testing performed.

Interventions

OTHERProvider-level and patient education at end of study

The provider level component will involve an email to each of the genitourinary medical oncologists at Johns Hopkins with their NGS testing rate from preliminary data and compare this rate to the mean. The initial email will also include the 2025 ASCO guideline recommending somatic testing in virtually all metastatic prostate cancer patients. Providers who do not have baseline NGS testing rates available will also be emailed. Providers will subsequently be emailed their updated NGS testing rate at the conclusion of the study period. Patients will also receive a one-page patient educational material (via email, or mail if no email on file) on advanced prostate cancer that includes education on somatic NGS testing at the end of the study period.

OTHERProvider-level and patient-level

In addition to the provider component, patients will also receive a one-page patient educational material (via email, or mail if no email on file) on advanced prostate cancer that includes education on somatic NGS testing. The email will be sent by the MyChart Recruitment Innovation team. Those without email on file will have the same message and attachment sent via mail by our study coordinator.