RecruitingNot ApplicableNCT07213258

CHAMPION: Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM


Sponsor

University of California, San Diego

Enrollment

100 participants

Start Date

Apr 24, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomized controlled trial is to pilot test new mobile health (mHealth) interventions to improve PrEP adherence among HIV-negative men who have sex with men (MSM) with mild to moderate methamphetamine use disorder (MUD). The CHAMPION intervention combines two mHealth tools-PrEPAPP and CBT4CBT-to address both HIV prevention and MUD treatment needs in this population. The study's specific aims are: * To evaluate the feasibility and acceptability of the CHAMPION intervention based on treatment retention and engagement rates. * To examine the preliminary efficacy the CHAMPION intervention to improve PrEP adherence, as measured by dried blood spot (DBS) tests compared to the waitlist control group.


Eligibility

Sex: MALEMin Age: 18 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called CHAMPION Intervention and a behavioral approach called Delayed CHAMPION Package for people with hiv, methamphetamine use disorder, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALCHAMPION Intervention

MHealth intervention to enhance PrEP adherence, combined with computer-administered cognitive behavioral therapy for a 6-month period for the intervention arm.

BEHAVIORALDelayed CHAMPION Package

Informational resources for first 3-months of study, followed by CHAMPION intervention for final 3-months.


Locations(1)

Center on Substance Use and Health

San Francisco, California, United States

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NCT07213258


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