RecruitingNot ApplicableNCT07213648

Modification of Threat Interpretation Bias to Reduce Anxiety in Neurodegenerative Movement Disorders (Aim 3)

Sponsor

University of Virginia

Enrollment

136 participants

Start Date

Nov 20, 2025

Study Type

INTERVENTIONAL

Conditions

Huntington Disease Parkinson Disease

Summary

The purpose of this study is to assess preliminary efficacy of a tailored cognitive bias modification for interpretation (CBM-I) app for reducing anxiety in Huntington's disease and Parkinson's disease.

Eligibility

Min Age: 21 Years

Inclusion Criteria2

Clinical diagnosis of Huntington's disease or Parkinson's disease (genetic diagnosis of HD also acceptable)
With anxiety symptoms (NeuroQoL Anxiety ≥12)

Exclusion Criteria6

Cognitive decline precluding ability to consent or complete the intervention (MoCA 5 min/telephone ≤11)
Unable to read and understand English
Does not have regular access to an internet-connected device, capable of downloading and installing the mobile application (i.e., tablet or iPhone running iOS 10 or later or an Android phone running Android 5.0 or later)
Not located in the USA
\<21 years old
Active suicidality based on the answer "yes" to questions 4, 5, or 6b of the Columbia-Suicide Severity Rating Scale (Screen version)