RecruitingNot ApplicableNCT07215533

Effects of HIIT vs. TRE on Type 2 Diabetes Risk

Differential Effects of HIIT vs. TRE on Type 2 Diabetes Risk in Youth and Younger Adults


Sponsor

Syracuse University

Enrollment

40 participants

Start Date

Mar 15, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The primary aim of this randomized controlled trial is to examine the effects of a 4-week high-intensity interval training (HIIT) and time-restricted eating (TRE) intervention on cardiometabolic biomarkers in adolescents and young adults.


Eligibility

Min Age: 14 YearsMax Age: 30 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two lifestyle interventions — high-intensity interval training (HIIT, short bursts of intense exercise) versus time-restricted eating (TRE, eating within a limited daily window) — to see which is more effective at reducing the risk of developing type 2 diabetes in teenagers and young adults with overweight or obesity. **You may be eligible if...** - You are between 14 and 17 years old with a BMI at or above the 85th percentile for your age and sex, OR - You are between 18 and 30 years old with a BMI of 25 or higher **You may NOT be eligible if...** - You have a chronic medical condition such as heart disease, diabetes, thyroid disease, lung disease, high blood pressure, kidney or liver problems, or autoimmune disease - You take certain daily medications that affect metabolism, blood pressure, or mood - You have a pacemaker Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALHigh-intensity interval training

The 4-week HIIT intervention will use a stationary bicycle performed 3 times/week (a total of 12 sessions over the 4-week), performing at the CRL. All participants will perform a 20-minute HIIT protocol (20 repetitions of 10-seconds work time followed by 50-seconds resting/active recovery for the first two weeks, and 10 repetitions of 20-seconds work time followed by 100-seonds resting/active recovery for the rest of two weeks; targeted 90% HRmax) after 5-minute warm-up (10% HRmax). The supervisor (PI: Joon Young Kim and/or Graduate researcher: Wonhee Cho) will provide encouragement and supervision for exercise adherence. Heart rate (Polar, Polar Electro Oy, Kempele, Finland) and rating of perceived exertion (RPE; detail described in the questionnaire section) will be recorded.

BEHAVIORALTime-restricted eating

Participants randomized into the TRE group will be instructed to consume all their calories within a 10-hour period. We will instruct participants that they can choose their time-window (early TRE \[7am - 5pm\] or late TRE \[1pm - 11pm\]), but it must remain constant for the duration of the study. Further, we will give no restrictions on the type of foods and/or the quantities individuals can consume. We will ask individuals to maintain their diet for the duration of the study. Participants will be given clear instructions on their diet and how to use the "MyFitnessPal" application. Participants will have their total daily energy requirement calculated using the following formula (Basal metabolic rate \[BMR\] x activity level) and will be told to eat that amount within their allotted time window. BMR will be calculated when participants have their body composition taken by the InBody. Participants will be told to start their 4-week diet the following day after visit.


Locations(1)

Syracuse University

Syracuse, New York, United States

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NCT07215533


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