RecruitingNot ApplicableNCT07220005

Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization

Sponsor

Duke University

Enrollment

24 participants

Start Date

Dec 10, 2025

Study Type

INTERVENTIONAL

Conditions

Stroke Arm Weakness as a Consequence of Stroke Upper Extremity Hemiparesis Upper Extremity Impairments Upper Extremity Weakness

Summary

The goal of this research study is to optimize the parameter of Low-Intensity Focused Ultrasound Stimulation (LIFUS) that is most effective in changing cortical excitability and motor learning skills in patients who suffered a stroke. The researchers hope to answer two questions. * with increasing power, would LIFUS be more effective? * with the same power, what LIFUS timing is the best For Aim 1, the study will compare 8, 4 W/cm\^2 to a zero(sham) stimulation to see if higher power is the better. For Aim 2, the study will compare 500 vs 1000 vs 2000 Hz "timing" to see which one is better.

Eligibility

Min Age: 21 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Low intensity focused ultrasound stimulation for people with arm weakness as a consequence of stroke, stroke, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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