A Study to Evaluate the Effect of KarXT on Urological Safety

This study is testing the urological safety of KarXT — a newer medication for schizophrenia — specifically looking at whether it causes bladder or urinary problems. People with schizophrenia who are currently stable (not in an acute episode) are eligible. **You may be eligible if...** - You are between 18 and 65 years old - You have a confirmed diagnosis of schizophrenia (based on psychiatric evaluation and the DSM-5 criteria) - Your schizophrenia is currently stable (PANSS total score ≤80 and CGI-S ≤4) - Your BMI is between 18 and 40 - You are willing to stop your current antipsychotic medications temporarily as instructed **You may NOT be eligible if...** - You have been newly diagnosed with schizophrenia - You have had another significant psychiatric diagnosis, alcohol or drug use disorder in the last 12 months - You have a significant medical condition that could affect your safety or the study results Talk to your doctor to see if this trial is right for you.