RecruitingNot ApplicableNCT07222241

Comparing Numbing Techniques in Mohs Micrographic Surgery

Randomized, Double-Blind, Placebo-Controlled Trial of Adjunct Nerve Blocks in Mohs Micrographic Surgery on the Face and Scalp

Sponsor

Abramson Cancer Center at Penn Medicine

Enrollment

150 participants

Start Date

Jan 27, 2026

Study Type

INTERVENTIONAL

Conditions

Skin Cancer Face Skin Cancer Scalp

Summary

This study seeks to determine whether adjunct regional nerve blocks reduce pain and anxiety in adult patients undergoing Mohs micrographic surgery for face and scalp skin cancers. Participants will be randomized to one of two arms: (1) placebo regional nerve block with sterile normal saline or (2) adjunct regional nerve block with lidocaine. All patients receive local infiltration with lidocaine for complete anesthesia.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Nerve Block and Placebo Nerve Block for people with skin cancer face and skin cancer scalp. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERNerve Block

0.45% lidocaine with 1:200,000 epinephrine

OTHERPlacebo Nerve Block

Sterile normal saline

Locations(1)

Perelman Center for Advanced Medicine

Philadelphia, Pennsylvania, United States

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NCT07222241

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