RecruitingNot ApplicableNCT07222280

Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy


Sponsor

Covenant Health, US

Enrollment

30 participants

Start Date

Jun 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to determine if utilizing the Quest AD-Detect blood test, while patient's are hospitalized for a cognitive diagnosis (such as delirium or encephalopathy), will result in an earlier diagnosis of underlying Alzheimer's disease. * Will this blood test have the ability to distinguish between Alzheimer's disease and other causes of cognitive impairment in the inpatient setting? * Neurology Clinic will complete a 6-month post-hospitalization follow up with patients who have had the Quest AD-Detect Alzheimer's Disease blood test completed while they were inpatient to discuss the risk assessment portfolio


Eligibility

Min Age: 60 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether hospitalized older adults who develop sudden confusion (delirium or encephalopathy) may have underlying Alzheimer's disease that hasn't been diagnosed yet. The goal is to catch early signs of Alzheimer's and understand the relationship between acute brain events and dementia. **You may be eligible if...** - You are between 60 and 90 years old - You have NOT been previously diagnosed with dementia - You are currently hospitalized and have been diagnosed with delirium, encephalopathy, or a similar condition thought to be caused by a medical issue (like infection, medication effects, or metabolic imbalance) **You may NOT be eligible if...** - You are under 60 years old - You have already been diagnosed with dementia or another organic cause of cognitive impairment Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTQuest AD-Detect blood test

Blood will be collected and sent for testing using the Quest AD-Detect blood test


Locations(6)

Cumberland Medical Center

Crossville, Tennessee, United States

Roane Medical Center

Harriman, Tennessee, United States

Fort Sanders Regional Medical Center

Knoxville, Tennessee, United States

Fort Loudon Medical Center

Lenoir City, Tennessee, United States

Methodist Medical Center

Oak Ridge, Tennessee, United States

LeConte Medical Center

Sevierville, Tennessee, United States

View Full Details on ClinicalTrials.gov

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NCT07222280


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