Encephalopathy Clinical Trials

7 recruiting

Encephalopathy Trials at a Glance

90 actively recruiting trials for encephalopathy are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 19 trials, with the heaviest enrollment activity in Boston, Houston, and Strasbourg. Lead sponsors running encephalopathy studies include Mayo Clinic, Boston Children's Hospital, and National Institute of Neurological Disorders and Stroke (NINDS).

Browse encephalopathy trials by phase

Treatments under study

About Encephalopathy Clinical Trials

Looking for clinical trials for Encephalopathy? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Encephalopathy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Encephalopathy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 90 trials

Recruiting

Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)

Progressive Multifocal Leukoencephalopathy
National Institute of Neurological Disorders and Stroke (NINDS)700 enrolled1 locationNCT01730131
Recruiting
Phase 2

Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study

Progressive Multifocal Leukoencephalopathy
National Institute of Neurological Disorders and Stroke (NINDS)24 enrolled1 locationNCT07511049
Recruiting
Phase 1

Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy

Multiple SclerosisProgressive Multifocal Leukoencephalopathy
National Institute of Neurological Disorders and Stroke (NINDS)15 enrolled1 locationNCT05849467
Recruiting

Predictive Value of aEEG and Cerebral Oxygenation on Neurological Outcomes in Newborns With Mild Hypoxic-Ischemic Encephalopathy

Hypoxic-Ischemic Encephalopathy Mild
Uludag University30 enrolled3 locationsNCT07393620
Recruiting
Phase 3

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

Developmental and Epileptic Encephalopathy
Longboard Pharmaceuticals320 enrolled109 locationsNCT06719141
Recruiting
Not Applicable

Autologous Bone Marrow Mononuclear Cell Transplantation Combined With Rehabilitation in Children With Sequelae of Hypoxic-Ischemic Encephalopathy or Intracranial Hemorrhage

Cerebral Palsy Hypoxic-Ischemic Encephalopathy Intracranial Hemorrhage
National Children's Hospital, Vietnam60 enrolled1 locationNCT07527104
Recruiting
Phase 4

Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis

CirrhosisAscitesPortal Vein Thrombosis+3 more
Asian Institute Of Medical Sciences220 enrolled1 locationNCT07521332
Recruiting
Phase 2

Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement

CirrhosisHepatic Encephalopathy
Hunter Holmes Mcguire Veteran Affairs Medical Center30 enrolled1 locationNCT06052176
Recruiting

Automating Delirium Severity in the ICU

DeliriumEncephalopathyIntensive Care Unit Delirium
Mayo Clinic400 enrolled1 locationNCT06172491
Recruiting

Observational Cohort Study of Chronic Viral Infection in the Central Nervous System

Immune Checkpoint InhibitorsProgressive Multifocal Leukoencephalopathy
Peking Union Medical College Hospital66 enrolled1 locationNCT07512518
Recruiting
Not Applicable

Healing Tiny Minds: Rural Recovery Through Virtual and Lived Experience Care

Cerebral PalsyPremature BirthNeurological Disorder+1 more
University of Wisconsin, Madison225 enrolled1 locationNCT06643598
Recruiting

Genetics of Neonatal Encephalopathy and Related Disorders

Neonatal EncephalopathyHypoxic Ischaemic Encephalopathy (HIE)
Boston Children's Hospital300 enrolled1 locationNCT07165938
Recruiting
Phase 2

TReatment for ImmUne Mediated PathopHysiology

Hepatic EncephalopathyAcute Liver FailureFulminant Hepatic Failure
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)163 enrolled24 locationsNCT04862221
Recruiting

CoMind Early Feasibility Study

EncephalitisTraumatic Brain InjuryStroke+6 more
CoMind Technologies Limited581 enrolled14 locationsNCT06368648
Recruiting

The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)

Cognitive DysfunctionLiver CirrhosisNeurocognitive Disorders+1 more
University of Malaya230 enrolled1 locationNCT07418008
Recruiting
Phase 2

T-cell Therapy in Patients With PML

Progressive Multifocal Leucoencephalopathy (PML)
Hannover Medical School23 enrolled6 locationsNCT06990087
Recruiting
Phase 1Phase 2

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

Epileptic Encephalopathy
Institut de Recherches Internationales Servier20 enrolled16 locationsNCT07227857
Recruiting

Biomarkers Study in Infants With Prior Neonatal Brain Injury

Healthy ParticipantsPremature BirthHIE - Hypoxic - Ischemic Encephalopathy+1 more
University of Wisconsin, Madison100 enrolled1 locationNCT07413900
Recruiting
Phase 3

Cooling in Mild Encephalopathy

Neonatal EncephalopathyNewborn Asphyxia
Imperial College London426 enrolled39 locationsNCT05889507
Recruiting

A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders

STXBP1 Encephalopathy With Epilepsy
European STXBP1 Consortium120 enrolled1 locationNCT06625112