RecruitingPhase 4NCT07223580

A Study Of Corticosteroid On Postoperative Pain After Ureteroscopy For Urinary Calculi

Evaluating The Role Of Corticosteroids In Post-Ureteroscopy Recovery For Urinary Calculi


Sponsor

Mayo Clinic

Enrollment

90 participants

Start Date

Jan 23, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research is to evaluate if corticosteroid (prednisone) after ureteroscopy and placement of the stent will help alleviate postoperative pain control in addition to other normal postoperative pain medications


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Patients who are diagnosed with kidney or ureteral stones confirmed on imaging (CT of the abdomen or pelvis) and who elect for definitive treatment via ureteroscopy with placement of ureteral stent.
  • Age 18 years or older
  • Patients of either gender
  • Patients of all ethnic backgrounds
  • Cable of giving informed consent
  • Capable and willing to fulfill the requirements of the study.

Exclusion Criteria8

  • History of chronic pain
  • Chronic use of opioids or other pain medication (\>12 weeks)
  • Known allergies to corticosteroids.
  • Known or suspected pregnancy
  • Inability to give informed consent or unable to meet requirements of the study for any reason.
  • Bilateral ureteroscopy
  • Current Corticosteroid Use
  • Diabetic patients who are insulin dependent

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Interventions

DRUGCorticosteroid

In addition to the standard of care postoperative ureteroscopy medication, participants will be given prednisone 25 mg orally, once a day for 5 days post-surgery.

OTHERPlacebo

In addition to the standard of care postoperative ureteroscopy medication, participants will be given a placebo pill orally, once a day for 5 days post-surgery.


Locations(1)

Mayo Clinic in Arizona

Scottsdale, Arizona, United States

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NCT07223580


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