Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

This study is collecting information on how patients with high-grade non-muscle-invasive bladder cancer (NMIBC) — cancer limited to the bladder lining — make decisions between continuing bladder-sparing treatments (like chemotherapy washes into the bladder) versus having surgery to remove the bladder. Researchers want to understand real-world patient preferences and outcomes. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with high-grade NMIBC (stage Tis, Ta, or T1) confirmed by pathology - You have a history of NMIBC and have received at least one bladder treatment (instillation or systemic therapy) in the past 12 months **You may NOT be eligible if...** - Your bladder cancer contains certain aggressive cell types (plasmacytoid or small cell/neuroendocrine) - You have a prior history of bladder removal surgery or radiation therapy for bladder cancer - You have ever had muscle-invasive or metastatic bladder cancer - You have untreated or active cancer in the urinary tract outside the bladder (such as the ureters or kidney) - You are currently incarcerated Talk to your doctor to see if this trial is right for you.