Splicing-based Predictive Learning for Individual Chemotherapy Evaluation in Colorectal Cancer

This study uses an artificial intelligence tool that analyzes how genes are "spliced" (processed) in tumor tissue to predict how well a patient responded to chemotherapy after surgery for colorectal cancer. It is a research study using stored tissue samples, not a treatment trial. **You may be eligible if...** - You have been diagnosed with stage II or III colorectal cancer (colon or rectal cancer) - You received standard chemotherapy after surgery to remove the tumor - There is stored tumor tissue (before chemotherapy) available for analysis - You are between 18 and 80 years old - There is enough follow-up data about your cancer outcomes **You may NOT be eligible if...** - You have inflammatory bowel disease - Your tumor tissue is not available or the sample quality is poor - You did not consent to tissue use Talk to your doctor to see if this trial is right for you.