RecruitingPhase 4NCT07228195

SGLT2i Therapy in Islet Transplantation (SIT)

Sponsor

University of Minnesota

Enrollment

40 participants

Start Date

Jul 21, 2026

Study Type

INTERVENTIONAL

Conditions

Diabetes Partial Islet Function TPIAT

Summary

This pilot clinical trial is designed to gather preliminary data on the efficacy and safety of empagliflozin, a diabetes drug in the sodium-glucose cotransporter 2 inhibitor (SGLT2i) class, in islet autotransplant recipients who have partial islet function.

Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Empagliflozin 10 MG Oral Tablet [Jardiance] and a drug called Empagliflozin 25 MG Oral Tablet for people with diabetes, partial islet function, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 70 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGEmpagliflozin 25 MG Oral Tablet

Empagliflozin, which is sold under the name of Jardiance, is FDA approved for patients 10 years of age and older to improve glycemic control in type 2 diabetes.

DRUGEmpagliflozin 10 MG Oral Tablet [Jardiance]

Empagliflozin, which is sold under the name of Jardiance, is FDA approved for patients 10 years of age and older to improve glycemic control in type 2 diabetes.

Locations(1)

University of Minnesota

Minneapolis, Minnesota, United States

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NCT07228195

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