RecruitingPhase 2NCT07230860

A Study of JNJ-95597528 in Participants With Moderate to Severe Atopic Dermatitis

A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of JNJ-95597528 for the Treatment of Adult Participants With Moderate to Severe Atopic Dermatitis

Sponsor

Janssen Research & Development, LLC

Enrollment

180 participants

Start Date

Jan 20, 2026

Study Type

INTERVENTIONAL

Conditions

Dermatitis Atopic

Summary

The purpose of this study is to assess how well JNJ-95597528 works compared to placebo in participants with moderate to severe atopic dermatitis (AD).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called JNJ-95597528 and a drug called Placebo for people with dermatitis atopic. The study is currently recruiting participants at 62 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGJNJ-95597528

JNJ-95597528 will be administered subcutaneously.

DRUGPlacebo

Placebo will be administered subcutaneously.

Locations(62)

First OC Dermatology

Fountain Valley, California, United States

University of California Los Angeles - Division of Dermatology

Los Angeles, California, United States

Southern California Dermatology

Santa Ana, California, United States

Driven Research LLC

Miami, Florida, United States

Arlington Dermatology

Rolling Meadows, Illinois, United States

Dawes Fretzin Clinical Research Group

Indianapolis, Indiana, United States

Henry Ford Health System

Detroit, Michigan, United States

Red River Research Partners LLC

Fargo, North Dakota, United States

Oregon Dermatology and Research Center

Portland, Oregon, United States

Clinical Research Philadelphia

Philadelphia, Pennsylvania, United States

Center for Clinical Studies

Houston, Texas, United States

Progressive Clinical Research

San Antonio, Texas, United States

Instituto Medico De Alta Complejidad (IMAC)

Buenos Aires, Argentina

CIPREC

Buenos Aires, Argentina

DOM Reumatología

Buenos Aires, Argentina

INAER - Investigación en Alergias y Enfermedades Respiratorias

Buenos Aires, Argentina

Derma Internacional S A

Buenos Aires, Argentina

Mautalen Salud e Investigacion

CABA, Argentina

Instituto de Investigaciones Clinicas Cordoba

Córdoba, Argentina

Centro de Investigaciones Clinicas CIC IESR

Rosario, Argentina

Centro Respiratorio Infantil

Rosario, Argentina

Centro de Investigaciones Medicas Tucuman

San Miguel de Tucumán, Argentina

Ceti - Centro de Estudos Em Terapias Inovadoras

Curitiba, Brazil

Hospital De Clinicas De Porto Alegre

Porto Alegre, Brazil

Instituto Brasil de Pesquisa Clinica

Rio de Janeiro, Brazil

Fundacao do ABC Centro Universitario FMABC

Santo André, Brazil

Pesquisare Saude

Santo André, Brazil

PSEG trials Centro de Pesquisa Clinica S A

São Paulo, Brazil

Dermatology Research Institute Inc

Calgary, Alberta, Canada

CCA Medical Research Corporation

Ajax, Ontario, Canada

SimcoDerm Medical and Surgical Dermatology Centre

Barrie, Ontario, Canada

Dr Wei Jing Loo Medicine Professional Corporation

London, Ontario, Canada

DermEdge Research

Mississauga, Ontario, Canada

Allergy Research Canada Inc.

Niagara Falls, Ontario, Canada

York Dermatology Clinic and Research Centre

Richmond Hill, Ontario, Canada

XLR8 Medical Research

Windsor, Ontario, Canada

China Japan Friendship Hospital

Beijing, China

Xiangya Hospital Central South University

Changsha, China

Hosp. of Chengde Medical University

Chengde, China

West China Hospital of Sichuan University

Chengdu, China

The First Affiliated Hospital of Sun Yat-Sen University

Guangzhou, China

Sanmenxia Central Hospital

Sanmenxia, China

Wuxi People s Hospital

Wuxi, China

The Second Affiliated Hospital of Xi'an Jiaotong University

Xi'an, China

ISA - Interdisciplinary Study Association GmbH

Berlin, Germany

Studienzentrum an der Hase GbR

Bramsche, Germany

Klinikum rechts der Isar an der Technischen Universitat Munchen

München, Germany

Universitaetsklinikum Muenster

Münster, Germany

Miyata Dermatology Clinic

Matsudo, Japan

Kume Clinic

Nishiku, Japan

Kindai University Hospital

Sakai, Japan

Teikyo University Hospital

tabashi City, Japan

Jitaikai Tachikawa dermatology clinic

Tachikawa, Japan

Nomura Dermatology Clinic

Yokohama, Japan

SOLUMED Centrum Medyczne

Poznan, Poland

Kaohsiung Veterans General Hospital

Kaohsiung City, Taiwan

Chang Gung Memorial Hospital

Kaohsiung City, Taiwan

Taipei Medical University Shuang Ho Hospital

New Taipei City, Taiwan

Chung Shan Medical University Hospital

Taichung, Taiwan

National Taiwan University Hospital

Taipei, Taiwan

Tri-Service General Hospital

Taipei, Taiwan

Linkou Chang Gung Memorial Hospital

Taoyuan, Taiwan

View Full Details on ClinicalTrials.gov

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NCT07230860

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