External Oblique Intercostal Plane Block for Liver Transplantation Recipient
External Oblique Intercostal Plane Block for Postoperative Analgesia in Liver Transplantation
Istinye University
60 participants
Dec 22, 2025
INTERVENTIONAL
Conditions
Summary
Postoperative pain management is one of the key factors in improving rehabilitation and accelerating recovery. The external oblique intercostal plane block can be used to provide abdominal wall analgesia for effective pain control in abdominal surgery. The aim of this study is to investigate the postoperative analgesic efficacy of the external oblique intercostal plane block in liver transplant recipients. The investigators will compare a group receiving the external oblique intercostal plane block with a control group to determine whether this block provides effective postoperative analgesia in liver transplant recipients.
Eligibility
Inclusion Criteria6
- Adult patients aged 18 to 75 years
- Scheduled for elective orthotopic liver transplantation (living or deceased donor)
- J-shaped or Mercedes incision planned
- ASA physical status III-IV
- Normal or acceptable coagulation profile at the time of block application (INR ≤ 1.5, platelet count ≥ 50,000/mm³, fibrinogen ≥ 150 mg/dL)
- Able to provide written informed consent
Exclusion Criteria7
- Coagulopathy at the time of block application (INR \> 1.5, platelet count \< 50,000/mm³, or fibrinogen \< 150 mg/dL)
- Known allergy or hypersensitivity to local anesthetics (amide group)
- Local infection or skin lesion at the block injection site
- Severe hemodynamic instability requiring high-dose vasopressor support
- Chronic opioid use (≥30 mg oral morphine equivalents per day for ≥30 days before surgery)
- Severe hepatic encephalopathy or cognitive impairment preventing use of PCA or pain scoring
- Emergency or re-transplantation surgery
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Interventions
External oblique intercostal plane block will be administered at the end of the surgery and after skin closure
Sham Block (Ultrasound probe placement without needle insertion or injection)
Locations(1)
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NCT07233083