RecruitingNCT07233941

Neuropsychological Profile Characterization in Patients With Migraine: Cognitive Functioning and Psychological Variables


Sponsor

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

Enrollment

150 participants

Start Date

Sep 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The overall objective is to define the neuropsychological profile of patients with migraine and evaluate its association with: psychological outcome measures (anxiety-depressive symptoms, pain catastrophizing, excessive worry, and coping strategies); the clinical profile of migraine; the prodromal, ictal, or interictal phase of the migraine attack; pharmacological therapy; and detoxification treatment in patients with migraine associated with medication overuse headache.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria6

  • Written informed consent.
  • Patients aged between 18 and 65 years.
  • Diagnosis of migraine according to the International Classification of Headache Disorders (ICHD-3) criteria.
  • Patients with a history of migraine for at least one year, to ensure the stability of the condition.
  • Stability of ongoing treatment for at least 3 months at baseline.
  • Understanding of the Italian language.

Exclusion Criteria3

  • Severe medical or psychiatric conditions (depression, schizophrenia, psychosis) documented by specific previous diagnoses.
  • A history of alcohol or drug abuse.
  • Primary sensory deficits.

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Locations(1)

Fondazione IRCCS Istituto Neurologico Carlo Besta

Milan, Italy

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NCT07233941


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