RecruitingPhase 4NCT07240077

Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal Septicemia

Beta-lactam Monotherapy Versus Beta-lactam Plus Levofloxacin for the Treatment of Streptococcal Bacteremia: A Multicenter, Randomized, Double-Blind, Pragmatic Trial


Sponsor

Mahidol University

Enrollment

165 participants

Start Date

Jan 8, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

A double-blind randomized controlled trial comparing beta-lactam plus levofloxacin versus beta-lactam monotherapy for the treatment of Streptococcal bacteremia


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Beta-lactam monotherapy and a drug called Beta-lactam plus levofloxacin combination therapy for people with bacteremia and streptococcus infection. The study is currently recruiting participants at 4 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGBeta-lactam monotherapy

Normal saline placebo

DRUGBeta-lactam plus levofloxacin combination therapy

IV Levofloxacin


Locations(4)

Faculty of Medicine Siriraj Hospital

Bangkok, Thailand

Maharaj Nakorn Chiang Mai Hospital

Chiang Mai, Thailand

Maharaj Nakhon Ratchasima

Nakhon Ratchasima, Thailand

Ratchburi Hospital

Ratchaburi, Thailand

View Full Details on ClinicalTrials.gov

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NCT07240077


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