RecruitingNot ApplicableNCT07241949

External Oblique Intercostal Block (EOICB) for Laparoscopic Cholecystectomy

Paravertebral Block or External Oblique Intercostal Block? A Comparative Analysis of Pain and Opioid Consumption After Laparoscopic Cholecystectomy: A Randomized Controlled Trial

Sponsor

Cukurova University

Enrollment

147 participants

Start Date

Dec 1, 2025

Study Type

INTERVENTIONAL

Conditions

Postoperative Pain Laparoscopic Cholecystectomy Patient-controlled Analgesia Paravertebral Block External Oblique Intercostal Plane Block

Summary

This single-center, prospective, randomized controlled trial aims to compare the effects of paravertebral block (PVB), external oblique intercostal (EOI) block, and intravenous patient-controlled analgesia (PCA) with tramadol on postoperative pain and opioid consumption in patients undergoing elective laparoscopic cholecystectomy. The primary endpoint is total tramadol consumption within 24 hours postoperatively. Secondary outcomes include pain scores, additional analgesic use, incidence of nausea/vomiting, mobilization time, and length of hospital stay.

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called External Oblique Intercostal Block (EOI Block), a procedure called Paravertebral Block (PVB), and others for people with external oblique intercostal plane block, laparoscopic cholecystectomy, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREParavertebral Block (PVB)

Ultrasound-guided bilateral thoracic paravertebral block performed after induction of general anesthesia using 0.25% bupivacaine, 20 mL per side (total 40 mL).

PROCEDUREExternal Oblique Intercostal Block (EOI Block)

Ultrasound-guided bilateral external oblique intercostal block performed after induction of general anesthesia with 0.25% bupivacaine, 20 mL per side (total 40 mL), injected between the external oblique and intercostal muscles.

DRUGTramadol IV Patient-Controlled Analgesia (PCA)

Intravenous patient-controlled analgesia (PCA) programmed to deliver tramadol with a maximum dose of 400 mg in 24 hours. Standard analgesia protocol includes IV paracetamol 1 g every 8 hours.