TC-G203 for Patients With GPC3-Positive Advanced Solid Tumors

This study is testing a new type of cancer treatment called TC-G203, which uses modified immune cells (T cells) engineered to find and destroy cancer cells that have a protein called GPC3 on their surface. This is being tested in people with advanced solid tumors that express GPC3 and have not responded to standard treatments. **You may be eligible if...** - You are 18 to 75 years old with an advanced solid tumor confirmed by biopsy - Your tumor tests positive for GPC3 (a protein marker confirmed by lab testing) - You have not responded to, or are no longer suitable for, standard therapy - You have at least one measurable tumor and are in good health (ECOG score 0 or 1) - You have adequate organ function and can provide blood for immune cell collection **You may NOT be eligible if...** - Your cancer originated in or has spread uncontrolled to the brain - You have had another cancer within the past 5 years - You have an active or significant autoimmune disease - You have HIV, a bleeding disorder, or active serious infection Talk to your doctor to see if this trial is right for you.