Rice Bran Supplementation for Radiation-Induced Oral Mucositis in Head and Neck Cancer
Effects of Rice Bran on Radiation-Induced Oral Mucositis in Patients With Head/Neck Cancer and Its Impact on the Quality of Life
Christina Milad Lobos
80 participants
Jan 15, 2023
INTERVENTIONAL
Conditions
Summary
This study aims to find out if taking rice bran supplements can help reduce the painful mouth sores (oral mucositis) that often occur in patients with head and neck cancer who receive radiation therapy. The trial will include adult patients undergoing radiation treatment. Participants will be given rice bran supplements during their therapy to see if it can lessen these side effects and improve their overall quality of life.
Eligibility
Inclusion Criteria5
- Male or female patients of age 18 years old tor more
- Patients with squamous cell carcinomas without metastases of other non-head and non-neck tumors.
- Patients undergoing radiotherapy with an ECOG performance status of 0, 1, or 2
- Patients who will receive IMRT delivered as radical or adjuvant therapy with or without concurrent chemotherapy
- Ready to provide written informed consent
Exclusion Criteria4
- Receiving any other approved or investigational anti-cancer agent than those specified in this study.
- Pregnant or breastfeeding female patients
- Patients who have oral lesions unrelated to treatment or cancer,
- Patients who are on drugs that could cause oral lesions or are using anticoagulants.
Interventions
Participants in the intervention group will receive a standardized dose of rice bran supplement administered orally each day throughout the course of their radiation therapy. The rice bran used is a natural dietary supplement rich in antioxidants and anti-inflammatory compounds, aimed at reducing the severity and duration of radiation-induced oral mucositis in patients with head and neck cancer.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07242859