RecruitingNot ApplicableNCT07242859

Rice Bran Supplementation for Radiation-Induced Oral Mucositis in Head and Neck Cancer

Effects of Rice Bran on Radiation-Induced Oral Mucositis in Patients With Head/Neck Cancer and Its Impact on the Quality of Life

Sponsor

Christina Milad Lobos

Enrollment

80 participants

Start Date

Jan 15, 2023

Study Type

INTERVENTIONAL

Conditions

Head &Amp; Neck Cancer Radiation-induced Oral Mucositis Head &Amp; Neck Squamous Cell Carcinoma

Summary

This study aims to find out if taking rice bran supplements can help reduce the painful mouth sores (oral mucositis) that often occur in patients with head and neck cancer who receive radiation therapy. The trial will include adult patients undergoing radiation treatment. Participants will be given rice bran supplements during their therapy to see if it can lessen these side effects and improve their overall quality of life.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether taking a rice bran supplement can reduce painful mouth sores (oral mucositis) — a very common and debilitating side effect of radiation therapy for head and neck cancer. **You may be eligible if...** - You are 18 years or older with squamous cell carcinoma of the head and neck (without spread to other organs) - You are undergoing or planned to undergo radiation therapy (IMRT) with or without chemotherapy - You are in reasonable health (ECOG score 0, 1, or 2) - You are able to provide written informed consent **You may NOT be eligible if...** - You are receiving other investigational cancer agents not specified in the study - You are pregnant or breastfeeding - You already have mouth sores unrelated to treatment or cancer - You are taking medications that can cause mouth sores or blood-thinning drugs (anticoagulants) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTrice bran

Participants in the intervention group will receive a standardized dose of rice bran supplement administered orally each day throughout the course of their radiation therapy. The rice bran used is a natural dietary supplement rich in antioxidants and anti-inflammatory compounds, aimed at reducing the severity and duration of radiation-induced oral mucositis in patients with head and neck cancer.

Locations(1)

German university in cairo

Cairo, Egypt

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NCT07242859

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