Comparison of Two Dosing Regimens of Intravenous Ketorolac for Post-Cesarean Pain Control
Comparison of Two Dosing Regimens of Intravenous Ketorolac for Post-Cesarean Pain Control: A Randomized Controlled Trial
Cairo University
126 participants
Dec 1, 2025
INTERVENTIONAL
Conditions
Summary
we aim to compare the analgesic efficacy of two intravenous ketorolac dosing regimens as part of a multimodal analgesic protocol that includes local wound infiltration for postoperative pain management after elective cesarean delivery.
Eligibility
Inclusion Criteria3
- full-term, singleton, pregnant women,
- aged 18-35 years,
- scheduled for elective cesarean delivery under spinal anesthesia
Exclusion Criteria8
- American Society of Anesthesiologists (ASA) physical class III or more
- multiple gestation. Patients with a history of allergy to any of the study drugs,
- renal impairment,
- gastrointestinal bleeding or ulceration
- inflammatory bowel disease,
- chronic pain or regular opioid use.
- Inability to comprehend the numeric pain scale (NRS) or the ObsQoR-11 score
- requirement for conversion to general anesthesia after spinal anesthesia
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Interventions
administered intravenously as 30 mg diluted in 10 mL of normal saline and injected over more than 15 seconds
administered intravenously as either 15 mg diluted in 10 mL of normal saline and injected over more than 15 seconds.
Locations(1)
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NCT07244757